ISSN 1662-4009 (online)

ey0020.7-3 | Gonadal Function and Fertility Issues in Childhood Cancer Survivors | ESPEYB20

7.3. Hypothalamic-pituitary-gonadal function, pubertal development and fertility outcomes in male and female medulloblastoma survivors: a single centre experience

E Stern , M Ben-Ami , N Gruber , A Toren , S Caspi , G Abebe-Campino , M Lurye , M Yalon , D Modan-Moses

Brief summary: This single-centre retrospective study analysed gonadal function in 62 patients (41 males) with medulloblastoma, treated between 1987 and 2021. The aim of the study was to characterize gonadal function and identify risk factors for gonadal failure.Survival rates of patients with medulloblastoma have significantly improved with the combination of many therapeutic approaches, such as adjuvant chemotherapy, craniospinal irradiation (CSI), sur...